Isikhumba se-PU ngokuvamile asinangozi emzimbeni womuntu. Isikhumba se-PU, esaziwa nangokuthi i-polyurethane leather, yimpahla yesikhumba yokwenziwa eyenziwe nge-polyurethane. Ngaphansi kokusetshenziswa okujwayelekile, isikhumba se-PU asikhiphi izinto eziyingozi, futhi imikhiqizo efanelekayo emakethe izophinde iphumelele ukuhlolwa ukuze kuqinisekiswe ukuphepha nokungabi nobuthi, ngakho-ke ingagqokwa futhi isetshenziswe ngokuzethemba.
Kodwa-ke, kwabanye abantu, ukuthintana isikhathi eside nesikhumba se-PU kungase kubangele ukungakhululeki kwesikhumba, njengokuluma, ububomvu, ukuvuvukala, njll., ikakhulukazi kubantu abanesikhumba esibucayi noma abangezwani nabo. Ngaphezu kwalokho, uma isikhumba sivezwa ezintweni ezingezwani nomzimba isikhathi eside noma isiguli sinezinkinga zokuzwela kwesikhumba, kungase kubangele ukuthi izimpawu zokungakhululeki kwesikhumba zibe zimbi nakakhulu. Kubantu abanemithethosisekelo ye-allergies, kunconywa ukugwema ukuthintana ngqo nesikhumba ngangokunokwenzeka futhi ugcine izingubo zihlanzekile futhi zomile ukuze unciphise ukucasuka.
Nakuba isikhumba se-PU siqukethe amakhemikhali athile futhi sinomthelela othile ocasulayo ku-fetus, akuyona into enkulu ukuyiphunga ngezikhathi ezithile isikhathi esifushane. Ngakho-ke, kwabesifazane abakhulelwe, asikho isidingo sokukhathazeka kakhulu mayelana nokuxhumana kwesikhashana nemikhiqizo yesikhumba ye-PU.
Ngokuvamile, isikhumba se-PU siphephile ngaphansi kwezimo ezijwayelekile zokusetshenziswa, kodwa kubantu abazwelayo, kufanele kuthathwe ukunakekelwa ukuze kuncishiswe ukuthintana okuqondile ukuze kuncishiswe izingozi ezingaba khona.